Adipocyte metabolism
Fat-cell size, lipogenesis and energy use in research models.
5-Amino-1-methylquinolinium · NNMT inhibitor
A small-molecule inhibitor of the enzyme NNMT, studied in fat-cell metabolism and NAD+ research.
Any 5 vials take 15% off the whole order. Mix compounds and sizes; applied automatically at checkout.
For laboratory research use only. Not for human or veterinary use.
5-Amino-1MQ (5-amino-1-methylquinolinium) is a small, membrane-permeable molecule that inhibits nicotinamide N-methyltransferase (NNMT). NNMT is highly expressed in adipose tissue and liver, where it methylates nicotinamide, a step that diverts it away from the NAD+ salvage pathway.
By blocking NNMT, 5-Amino-1MQ is studied for its effects on intracellular NAD+ levels, adipocyte metabolism and energy expenditure in preclinical models. It is a research tool for the NNMT pathway, and is often considered alongside NAD+ itself.
Where 5-Amino-1MQ appears in laboratory and preclinical research.
Fat-cell size, lipogenesis and energy use in research models.
Preserving nicotinamide for NAD+ regeneration.
Metabolic-rate endpoints in preclinical studies.
The enzyme's role in methylation and metabolism.
| Product | 5-Amino-1MQ |
|---|---|
| Also known as | 5-Amino-1-methylquinolinium · NNMT inhibitor |
| Class | Small molecule (methylquinolinium), NNMT inhibitor |
| Form | Lyophilized (freeze-dried) powder |
| Fill sizes | 5mg |
| Purity | 99%+, verified by HPLC for every lot |
| Storage | Lyophilized: −4 °F, protected from light. Reconstituted: 36–46 °F. |
| Documentation | Certificate of analysis on request; lot number supplied in writing with every order |
| Intended use | Laboratory research only. Not for human or veterinary use. |
5-Amino-1MQ is a small-molecule NNMT inhibitor used in laboratory research on fat-cell metabolism and NAD+ pathways.
No. It is a small molecule, supplied lyophilized in a vial like the rest of the catalog.
No. 5-Amino-1MQ is sold strictly for laboratory research use. It is not a drug, food or supplement, and is not for human or veterinary use or for diagnosing, treating or preventing any condition.
Research use only. All Vivid DNA products are sold strictly for laboratory research. They are not drugs, foods, cosmetics or supplements, are not for human or veterinary use, and are not intended to diagnose, treat, cure or prevent any disease. Statements on this page describe published and preclinical research and have not been evaluated by the Food and Drug Administration.