Mitochondrial energy
Redox balance and ATP production in cellular and preclinical models.
Cellular
Cellular · research compound
NAD+
Nicotinamide adenine dinucleotide · NAD · β-NAD
The coenzyme at the centre of cellular energy metabolism, studied in mitochondrial, sirtuin, DNA-repair and cellular-ageing research.
$78 / vial
Volume pricingMix any vials. Save up to 30%.
5vials15% off
6vials20% off
7+vials30% off
Any 5 vials take 15% off the whole order. Mix compounds and sizes; applied automatically at checkout.
For laboratory research use only. Not for human or veterinary use.
What is NAD+?
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in every living cell. It shuttles electrons in the redox reactions of glycolysis, the citric acid cycle and oxidative phosphorylation, and it is consumed as a substrate by sirtuins, PARPs and CD38, enzymes involved in gene regulation, DNA repair and signalling.
Cellular NAD+ levels decline with age in many model systems, which has made NAD+ a focus of research into mitochondrial function, metabolic regulation and cellular senescence. Researchers use it to study NAD+ metabolism directly and alongside precursors and pathway modulators such as 5-Amino-1MQ.
Read the full research overview: how it works, studies and references →
Research applications
Where NAD+ appears in laboratory and preclinical research.
Sirtuin signalling
NAD+-dependent deacetylases and their role in metabolic regulation.
DNA repair
PARP activity and genome-maintenance pathways that consume NAD+.
Cellular ageing
Age-associated NAD+ decline and senescence in model systems.
Specifications
| Product | NAD+ |
|---|---|
| Also known as | Nicotinamide adenine dinucleotide · NAD · β-NAD |
| Class | Coenzyme (dinucleotide) |
| Form | Lyophilized (freeze-dried) powder |
| Fill sizes | 500mg |
| Purity | 99%+, verified by HPLC for every lot |
| Storage | Lyophilized: −4 °F, protected from light. Reconstituted: 36–46 °F. |
| Documentation | Certificate of analysis for lot VD-NAD500-2610: report VPL-261008-6019 ↗. Every published certificate is on our lab reports page. Lot number supplied in writing with every order |
| Intended use | Laboratory research only. Not for human or veterinary use. |
NAD+ FAQ
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme involved in cellular energy production and a substrate for sirtuin and PARP enzymes. It is used here for laboratory research.
Why is NAD+ studied in ageing research?
NAD+ levels fall with age in many model organisms, so researchers study how that decline relates to mitochondrial function and cellular senescence.
Is NAD+ for human use?
No. NAD+ is sold strictly for laboratory research use. It is not a drug, food or supplement, and is not for human or veterinary use or for diagnosing, treating or preventing any condition.
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Research use only. All Vivid DNA products are sold strictly for laboratory research. They are not drugs, foods, cosmetics or supplements, are not for human or veterinary use, and are not intended to diagnose, treat, cure or prevent any disease. Statements on this page describe published and preclinical research and have not been evaluated by the Food and Drug Administration.