Cognition
Learning and memory endpoints in animal models.
Cognitive
Cognitive · research compound
Semax
ACTH (4-10) analog · Met-Glu-His-Phe-Pro-Gly-Pro
A synthetic analog of an ACTH fragment, studied for cognition, neuroprotection and neurotrophic signalling.
$98 / vial
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5vials15% off
6vials20% off
7+vials30% off
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For laboratory research use only. Not for human or veterinary use.
What is Semax?
Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) based on the 4-10 fragment of adrenocorticotropic hormone (ACTH), extended with a Pro-Gly-Pro sequence for stability. The fragment keeps neuroactive properties of ACTH without its hormonal effects on the adrenal glands.
Research on Semax focuses on learning and memory in animal models, neuroprotection in models of cerebral ischaemia, and its effects on brain-derived neurotrophic factor (BDNF) and its receptor. It is frequently studied together with Selank.
Read the full research overview: how it works, studies and references →
Research applications
Where Semax appears in laboratory and preclinical research.
Neuroprotection
Neural survival in cerebral ischaemia and injury models.
BDNF signalling
Brain-derived neurotrophic factor and TrkB receptor expression.
Neuropeptide research
Non-hormonal activity of ACTH-derived fragments.
Specifications
| Product | Semax |
|---|---|
| Also known as | ACTH (4-10) analog · Met-Glu-His-Phe-Pro-Gly-Pro |
| Class | Synthetic heptapeptide, ACTH (4-10) analog |
| Form | Lyophilized (freeze-dried) powder |
| Fill sizes | 10mg |
| Purity | 99%+, verified by HPLC for every lot |
| Storage | Lyophilized: −4 °F, protected from light. Reconstituted: 36–46 °F. |
| Documentation | Certificate of analysis for lot VD-SX10-2610: report VPL-261008-5023 ↗. Every published certificate is on our lab reports page. Lot number supplied in writing with every order |
| Intended use | Laboratory research only. Not for human or veterinary use. |
Semax FAQ
What is Semax?
Semax is a synthetic ACTH (4-10) analog heptapeptide used in laboratory research on cognition and neuroprotection.
Does Semax have hormonal activity?
The ACTH (4-10) fragment it is based on lacks the adrenal-stimulating activity of full-length ACTH, which is why it is studied for neural effects.
Is Semax for human use?
No. Semax is sold strictly for laboratory research use. It is not a drug, food or supplement, and is not for human or veterinary use or for diagnosing, treating or preventing any condition.
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Research use only. All Vivid DNA products are sold strictly for laboratory research. They are not drugs, foods, cosmetics or supplements, are not for human or veterinary use, and are not intended to diagnose, treat, cure or prevent any disease. Statements on this page describe published and preclinical research and have not been evaluated by the Food and Drug Administration.