Energy balance
Body-weight regulation, food intake and energy expenditure in preclinical models.
Metabolic
Metabolic · research compound
GLP-3RT
Triple-receptor agonist · GLP-1 / GIP / glucagon agonist · GLP-3 research peptide
A single synthetic peptide that acts on three metabolic receptors at once, GLP-1, GIP and glucagon, used as a reference compound in energy-balance and glucose-regulation research.
$104 / vial
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5vials15% off
6vials20% off
7+vials30% off
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For laboratory research use only. Not for human or veterinary use.
What is GLP-3RT?
GLP-3RT is a synthetic peptide agonist engineered to activate the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and glucagon receptors from one molecule. Mono-agonists engage one of these pathways and dual agonists two; a triple agonist lets researchers study all three together, including the energy-expenditure signalling associated with the glucagon receptor.
That profile makes GLP-3RT a common tool in metabolic research: studies of body-weight regulation and food intake in animal models, glucose homeostasis and insulin secretion, hepatic lipid handling, and comparative receptor pharmacology against single and dual agonists such as tirzepatide.
Read the full research overview: how it works, studies and references →
Research applications
Where GLP-3RT appears in laboratory and preclinical research.
Glucose homeostasis
Insulin secretion and glycaemic control via incretin receptor signalling.
Hepatic lipid metabolism
Liver fat and lipid-handling endpoints linked to glucagon receptor activity.
Receptor pharmacology
Comparing triple agonism with mono- and dual-agonist reference compounds.
Specifications
| Product | GLP-3RT |
|---|---|
| Also known as | Retatrutide · triple-receptor agonist · GLP-1 / GIP / glucagon agonist · GLP-3 research peptide |
| Class | Synthetic peptide, triple incretin / glucagon receptor agonist |
| Form | Lyophilized (freeze-dried) powder |
| Fill sizes | 10mg, 30mg, 60mg |
| Purity | 99%+, verified by HPLC for every lot |
| Storage | Lyophilized: −4 °F, protected from light. Reconstituted: 36–46 °F. |
| Documentation | Certificate of analysis for lot VD-RT10-2610: report VPL-261008-2849 ↗. Every published certificate is on our lab reports page. Lot number supplied in writing with every order |
| Intended use | Laboratory research only. Not for human or veterinary use. |
GLP-3RT FAQ
What is GLP-3RT?
GLP-3RT is a synthetic research peptide that activates the GLP-1, GIP and glucagon receptors. It is used in laboratory studies of metabolism, energy balance and glucose regulation.
How does GLP-3RT differ from tirzepatide?
Tirzepatide is a dual agonist acting on the GLP-1 and GIP receptors. GLP-3RT adds glucagon receptor activity, so it is studied as a triple agonist.
Is GLP-3RT for human use?
No. GLP-3RT is sold strictly for laboratory research use. It is not a drug, food or supplement, and is not for human or veterinary use or for diagnosing, treating or preventing any condition.
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Research use only. All Vivid DNA products are sold strictly for laboratory research. They are not drugs, foods, cosmetics or supplements, are not for human or veterinary use, and are not intended to diagnose, treat, cure or prevent any disease. Statements on this page describe published and preclinical research and have not been evaluated by the Food and Drug Administration.